Introduction:
METODIP is a clinically effective line of Metoprolol-based extended-release tablets, designed for long-term management of hypertension, angina pectoris, and other cardiovascular conditions. It also includes a combination formulation with Amlodipine, enhancing efficacy for patients requiring dual antihypertensive therapy. The ER (Extended Release) formulations offer once-daily dosing, ensuring steady plasma concentration and improved patient adherence.
Available in blister packaging (10 x 10 tablets) for dosage accuracy and shelf-life preservation.
Product Variants & Composition:
METODIP-12.5 ER
Composition: Metoprolol 12.5 mg (Extended Release)
Packaging: Blister | 10 x 10 Tablets
METODIP-25 ER
Composition: Metoprolol 25 mg (Extended Release)
Packaging: Blister | 10 x 10 Tablets
METODIP-50 ER
Composition: Metoprolol 50 mg (Extended Release)
Packaging: Blister | 10 x 10 Tablets
METODIP-A
Composition: Metoprolol 50 mg + Amlodipine 5 mg
Packaging: Blister | 10 x 10 Tablets
Key Benefits:
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Metoprolol ER: Provides sustained β1-selective adrenergic blockade with 24-hour control of blood pressure and heart rate.
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Reduces myocardial oxygen demand, controlling angina and improving exercise tolerance.
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Helps in secondary prevention of myocardial infarction and managing heart failure symptoms.
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Combination variant (METODIP-A) offers synergistic BP control via β-blockade and calcium channel blockade.
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Once-daily dosing improves compliance, especially in chronic cardiac patients.
Indications:
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Essential hypertension
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Stable angina pectoris
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Heart failure (with reduced ejection fraction)
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Post-myocardial infarction secondary prevention
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Palpitations and arrhythmias (especially supraventricular)
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Dual therapy with METODIP-A in patients unresponsive to monotherapy
Dosage & Administration:
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Start with the lowest effective dose (e.g., 12.5–25 mg daily), titrate based on clinical response.
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METODIP-A is typically given once daily with or without food.
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Regular monitoring of blood pressure, heart rate, and renal function is recommended.
Precautions & Warnings:
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Avoid abrupt withdrawal; taper gradually to prevent rebound hypertension or angina.
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Use caution in asthma/COPD, bradycardia, or heart block.
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Not advised in acute heart failure or cardiogenic shock.
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Monitor for signs of hypotension or dizziness, especially in elderly patients.
Possible Side Effects:
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Fatigue, dizziness, bradycardia
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Cold extremities, insomnia
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Rare: AV block, hypotension, bronchospasm (in predisposed individuals)
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Peripheral edema (with Amlodipine combination)
Conclusion:
The METODIP range offers a reliable and clinically validated solution for cardiovascular management. From monotherapy to fixed-dose combinations, METODIP delivers enhanced cardiovascular protection with sustained action and minimal side effects.
Note : Always Consult a physician before taking any medication, and do not rely solely on this information for medical advice.
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