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DUPIN

TAB DUPIN-2.5 (Amlodipine 2.5 mg ) ALU-ALU 10 X 10
TAB DUPIN-5 (Amlodipine 5 mg) ALU-ALU 10 X 10
TAB DUPIN-AT (Amlodipine 5 mg + Atenolol 50 mg ) ALU-ALU 10 X 10
TAB DUPIN-L (Amlodipine 5 mg + Losartan 50 mg ) BILSTER 10 X 10
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Introduction:

DUPIN is a comprehensive range of antihypertensive medications formulated by Daksh Diabetic & Cardiac Care, designed to effectively manage high blood pressure and associated cardiovascular conditions. The DUPIN series includes monotherapy options with Amlodipine and combination therapies with Atenolol or Losartan, catering to diverse patient needs. Each variant is packaged in ALU-ALU or blister packs (10 x 10 tablets) to ensure optimal drug stability and shelf life.

Product Range & Benefits:

  1. DUPIN-2.5
    Composition: Amlodipine 2.5 mg
    Packaging: ALU-ALU, 10 x 10 Tablets
    Use: Initiation of therapy in patients with mild hypertension or those sensitive to higher doses.

    Key Benefits:

    • Gentle blood pressure reduction

    • Minimizes risk of hypotension in sensitive individuals

    • Suitable for elderly patients or those with hepatic impairment

  2. DUPIN-5
    Composition: Amlodipine 5 mg
    Packaging: ALU-ALU, 10 x 10 Tablets
    Use: Monotherapy for patients requiring standard-dose calcium channel blocker therapy.

    Key Benefits:

    • Effective in controlling moderate hypertension

    • Improves angina symptoms by dilating coronary arteries

    • Once-daily dosing enhances patient compliance

  3. DUPIN-AT
    Composition: Amlodipine 5 mg + Atenolol 50 mg
    Packaging: ALU-ALU, 10 x 10 Tablets
    Use: Combination therapy for patients requiring both calcium channel blocker and beta-blocker effects.

    Key Benefits:

    • Synergistic action for better blood pressure control

    • Reduces heart rate and myocardial oxygen demand

    • Ideal for patients with coexisting hypertension and angina

  4. DUPIN-L
    Composition: Amlodipine 5 mg + Losartan 50 mg
    Packaging: Blister, 10 x 10 Tablets
    Use: Dual therapy for patients needing both calcium channel blocker and angiotensin receptor blocker (ARB) effects.

    Key Benefits:

    • Enhanced antihypertensive efficacy

    • Provides renal protection, beneficial in diabetic hypertensive patients

    • Reduces risk of stroke and myocardial infarction

Indications:

  • Management of primary hypertension

  • Treatment of angina pectoris

  • Adjunct therapy in patients with coexisting cardiovascular conditions

  • Renal protection in hypertensive patients with diabetes (specifically with DUPIN-L)

Dosage and Administration:

  • DUPIN-2.5 / DUPIN-5: One tablet once daily, with or without food.

  • DUPIN-AT / DUPIN-L: One tablet once daily, preferably at the same time each day.

Administration Tips:

  • Swallow the tablet whole with water; do not crush or chew.

  • Consistent daily intake is essential for optimal blood pressure control.

  • Follow your doctor’s instructions regarding dosage adjustments.

Precautions & Warnings:

  • Use cautiously in patients with hepatic or renal impairment.

  • Monitor blood pressure regularly to avoid hypotension.

  • DUPIN-AT should be used with caution in patients with bronchospastic diseases.

  • DUPIN-L may increase serum potassium levels; monitor electrolytes periodically.

  • Not recommended during pregnancy or lactation unless specifically advised by a healthcare provider.

Possible Side Effects:

  • Dizziness or lightheadedness

  • Peripheral edema (swelling of ankles or feet)

  • Fatigue

  • Nausea

  • Bradycardia (especially with DUPIN-AT)

  • Hyperkalemia (especially with DUPIN-L)

Note: This list is not exhaustive. Consult a healthcare professional for a complete list of potential side effects.

Conclusion:

The DUPIN range—comprising DUPIN-2.5, DUPIN-5, DUPIN-AT, and DUPIN-L—offers versatile and effective antihypertensive solutions tailored to individual patient needs. Whether as monotherapy or combination therapy, DUPIN ensures reliable blood pressure control, cardiovascular protection, and improved patient adherence through once-daily dosing.

Note : Always Consult a physician before taking any medication, and do not rely solely on this information for medical advice.

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